Isabelle Boutron is professor of epidemiology at the Université de Paris and head of the methods team at Inserm’s Centre of Research in Epidemiology and Statistics. She is deputy director of the Equator Network, director of Cochrane France and co-convener of the bias methods group of the Cochrane Collaboration. Her research focuses on meta-research, methodological issues of assessing interventions (blinding, external validity and complex interventions), transparency, reporting guidelines development and implementation, and research synthesis. She is also coordinating the Methods in Research on Research Projects, an innovative and ambitious joint doctoral training program funded by Marie Skłodowska-Curie Actions, dedicated to the field of clinical research.