Isabel Casillas Guzman is an entrepreneur, economic development expert, and former Administrator of the U.S. Small Business Administration. She led the SBA through the COVID-19 crisis and economic recovery – overseeing $1.2T in pandemic relief and a $500B portfolio, driving historic reforms that expanded access to capital and contracting, and serving as the voice for America’s 34 million small businesses. Her tenure ushered in a new era of government innovation – modernizing programs, realigning operations, and unlocking record levels of investment. Previously, she served as California’s top small business official and has founded and advised multiple ventures. Isabel continues to champion entrepreneurship, innovation, and resilient economic growth for the future.

Guzman briefed National Press Foundation fellows in April 2026: Former SBA Chief Guzman: Pandemic Survival Lessons Aiding Local Businesses Facing New Tests.